A lack of vitamin B12 in the body can lead to vitamin deficiency anemia 1 2 4. Vitamin B12 levels are measured through a vitamin B12 level blood test, also referred to as a cobalamin test, according to MedlinePlus. Food sources of vitamin B-12 include poultry, meat, fish and dairy products. A simple blood test can be performed in your doctor’s office to test the levels of vitamin B12 in your blood. Some medications can interfere with this test. by: Kerri Knox, RN, The Immune Queen You cannot get an accurate blood test while on Vitamin B12 supplements. If after the test, the doctor would identify that you have a little amount of the vitamin in your body, you may be advised to take in supplements to produce the balance. This test is most often done when other blood tests suggest a condition called megaloblastic anemia. Normal vitamin B12 levels vary throughout different labs. This makes it nearly impossible to overdose on the nutrient. There is a low-cost blood test available that can detect this genetic defect. Learn more here. Body cells need vitamin B12 to use folate. High Serum B12 Can Be Caused By A Functional B12 Deficiency. “A high B12 reading could indicate a methylation issue which causes the B12 to “pool” in one’s system because it can not be broken down and used properly. My blood test cam back with a Folate Level of 28.1 ng/mL on a range of 3.1-17.5 and my B12 was 1,408.0 pg/mL on a range of 193.0-986.0. So if vitamin B12 levels are very low, folate can't be used by the cells, and high levels of it may build up in the blood. For the study, Ohio State University Comprehensive Cancer Center researchers examined 77,000 patients between the ages of 50 and 76 over a 10-year period. Vitamin B12 is an essential nutrient, important in nerve and blood cell health, and most people obtain enough of it in food. It has a short life and drops much faster than total vitamin B12 when your B12 supplies start running low. Vitamin B12 test measures how much of the vitamin is in your blood. Consuming large amounts of the vitamin won’t make you sick. A study published in the Journal of Clinical Oncology in 2017 found that consumption of too much vitamin B6 and vitamin B12 could greatly increase the chance of developing lung cancer in men. This means that there is enough B12 in the body, but the cells are not able to use it, so they export it back to the blood, and it builds up there, bound to haptocorrin. But if you take supplements, you might ingest more than your body needs. I have not spoken to the doctor about this yet but will be in two weeks. If a significant amount of the vitamin B12 in your blood is inactive, a blood test may show that you have normal B12 levels, even though your body cannot use much of it. As a result, you could be anemic. The active B12 test is unlikely to help unless you're trying to figure out why you have symptoms of a B12 deficiency despite such high serum levels. Vitamin B-12 is indirectly responsible for raising your blood iron level to keep it in a healthy range. Vitamin B-12 (cobalamin) is a water-soluble vitamin that plays essential roles in red blood cell formation, cell metabolism, nerve function and the production of DNA. Vitamin B12 is generally well-tolerated, even in doses well above the recommended dietary allowance (RDA), which is 2.4 micrograms daily for adult men and women.Because vitamin B12 is a water soluble vitamin and is excreted in the urine when consumed in excess, it's difficult to overdose on this essential nutrient. It aids the nerve cells, the RBCs and is even used to produce DNA in the cells. Pee may be bright yellow because it’s a water-soluble vitamin. Having too much folic acid in the blood is not a dangerous condition and does not cause other health issues. After a week, the haptocorrin-bound B12 is imported by the liver and recycled via the bile to the gut. This happens when there is problem with the working of the liver, or there is blood disease. Vitamin B12 is one of the components for correct red blood formation. This can occur when the stomach makes less of the substance the body needs to properly absorb vitamin B12. Pernicious anemia is a form of megaloblastic anemia caused by poor vitamin B12 absorption. If a ferritin test shows higher than normal levels, it could indicate that you have a condition that causes your body to store too much iron. "Vitamin B12 is crucial for a well-functioning brain and nervous system. It is a fundamental element in the metabolic process of proteins, it helps to the formation of red blood cells and it is also necessary for … Both of these levels appear to be well above the ranges. It is a vitamin that dissolves in water (water-soluble). Reasons for deficiency may include reasons like too much alcohol and poor diet. The relationship among vitamin B-12, folate and iron is a good example of the complex way in which some essential nutrients help keep your body healthy. If you are trying for that then an MMA test is more likely to prove useful (although both are highly likely to give normal results). On top of that, we know that only a small percentage of vitamin B12 taken orally is actually absorbed. Hi, Question regarding my 2.5 year old son. Increased vitamin B12 levels are uncommon, because excess vitamin B12 is usually eliminated with urine. There is no risk of cancer from high B12 levels from SUPPLEMENTS. Once the test is performed, your doctor will discuss the results with you. High folate levels can also mean a vitamin B12 deficiency. A high level of folic acid or folate in the blood indicates a person eats a diet that is high in folic acid, takes vitamins, takes folic acid pills or has a vitamin B12 deficiency, states WebMD. Pernicious anemia is a form of megaloblastic anemia caused by poor vitamin B12 absorption. Dr said everything looked normal, but when he showed me the results the vit B12 was flagged as "high" at around 1400. I Vlog trough my journey of trying to overcome Rheumatoid Arthritis with natural means. Vitamin B12 is a very important vitamin for the body. Inactive analogues of B12 (transcobalamin I and III) may represent as much as 80% of your blood levels. Everyone needs vitamin B-12, and most people get enough through their diet. I questioned him about it and he said that was good not bad. But a folate test is not a reliable way to test for a vitamin B12 deficiency. This test is most often done when other blood tests suggest a condition called megaloblastic anemia. Low values This can occur when the stomach makes less of the substance the body needs to properly absorb vitamin B12. The serum vitamin B12 blood test isn’t reliable. It is MTHFR. Vitamin B12 is a water-soluble vitamin, which means that when we ingest too much of it, the excess amounts are flushed out of the body through urine. It can help diagnosis a specific type of anemia and other problems. Symptoms of too much vitamin B12 Dr Thornber said one of the signs of too much vitamin B12 is urine discolouration. Does Vitamin B-12 Raise Iron Levels in Blood?. Ignore the blood test. A 2008 study published by the American Academy of Neurology with 107 participants over 61-years-old, found that the brain volume lost over five years was greater for people with lower B12 levels in the blood. Vitamin B-12 is also added to some foods and is available as an oral supplement. Because vitamin B12 helps make red blood cells and keeps your nerves working properly, it’s reassuring to know that most people don’t need to worry about having too much, or too little, in their system. It measures the total amount of B12 in the blood, not distinguishing between active and inactive forms of B12. Consequently, an overdose of B12 is often useful, needed to achieve the desired elevation in B12 blood levels. No research has yet found any side effects from taking too much vitamin B-12. High levels of Vitamin B12 may be too much of a good thing. Vitamin B12 Overdose: the Vitamin B Complex. Active vitamin B12 makes up 6 – 20% of your total blood vitamin B12 levels [28, 29]. He recently had some blood work done a CBC, iron test, and vit B12, thyroid test. It helps form red blood cells. There are some types of blood test that may help determine if the vitamin B12 in your blood can … Though high Vitamin B12 in blood levels is a rare occurrence, it does occur. Many vitamin B-12 supplements contain much more of the vitamin than the body needs. The former may cause vascular dilation, itching, nausea, headache and allergies. I partnered up with Oxford Biosciences to give you the best vitamin B12 supplement.. Vitamin B12 is great. Although total vitamin B12 is the most commonly used test, these 2 additional markers may provide important insight into your B12 status in specific cases. The GP assured me that I don't have any of these things, as my kidney and liver function tests all come out fine and so do my white blood … Deficiency in folic acid Excess Vitamin Supplements The most obvious cause of an elevated vitamin B12 level is taking too much of the vitamin … However, if you google "excess vitamin B12 in the blood" you get a whole load of worrying suggestions, like liver or kidney disease and a long list of leukaemias and cancers. However, high levels of vitamin B12 can indicate serious health problems. It is crucial to the synthesis and repair of DNA and the myelin sheath, a layer safeguarding our nerves. Learn about the side effects of taking too much. 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